Description:
7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine is used to prepare varenicline, which is a smoking cessation. Varenicline is a nicotinic receptor partial agonist.
- Molecular Weight: 307.27
- Molecular Formula: C15H12F3N3O
Purity: ≥ 95%
Canonical SMILES:
C1C2CN(CC1C3=CC4=NC=CN=C4C=C23)C(=O)C(F)(F)F
InChI:
InChI=1S/C15H12F3N3O/c16-15(17,18)14(22)21-6-8-3-9(7-21)11-5-13-12(4-10(8)11)19-1-2-20-13/h1-2,4-5,8-9H,3,6-7H2
InChIKey: XDLHBWIAJAKYKF-UHFFFAOYSA-N
- Boiling Point: 491.9±45.0 °C (Predicted)
- Melting Point: 164-166 °C
- Solubility: Soluble in Methanol, DMSO
- Appearance: Pink Solid
- Storage: 2-8 °C
Synonyms:
2,2,2-Trifluoro-1-(6,7,9,10-tetrahydro-6,10-methano-8H-pyrazino[2,3-h][3]benzazepin-8-yl)ethanone; 1-(9,10-Dihydro-6H-6,10-methanoazepino[4,5-g]quinoxalin-8(7H)-yl)-2,2,2-trifluoroethanone; 6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine,7,8,9,10-tetrahydro-8-(trifluoroacetyl)-(9CI); Varenicline Impurity 16
More details are to be found on supplier website
